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The case for randomized controlled trials to assess the impact of clinical information systems

The case for randomized controlled trials to assess the impact of clinical information systems

State of Florida v. George Zimmerman was a criminal prosecution of George Zimmerman on the charge of second-degree murder stemming from the shooting of Trayvon Martin on February 26, On April 11, , George Zimmerman was charged with second-degree murder in the shooting death of year-old Trayvon Martin. In support of the charges, the State filed an affidavit of probable cause, stating that Zimmerman profiled and confronted Martin and shot him to death while Martin was committing no crimes. After sixteen hours of deliberations over the course of two days, on July 13, , the six-person jury rendered a not guilty verdict on all counts. De la Rionda was an Assistant State Attorney in Corey's office and had been a prosecutor for 29 years.
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Suspect in Nia Wilson’s Murder Cleared to Stand Trial

There is a persistent view of a significant minority in the medical informatics community that the randomized controlled trial RCT has a limited role to play in evaluating clinical information systems. A common reason voiced by skeptics is that these systems are fundamentally different from drug interventions, so the RCT is irrelevant. There is an urgent need to promote the use of RCTs, given the shift to evidence-based policy and the need to demonstrate cost-effectiveness of these systems. The authors suggest returning to first principles and argue that what is required is clarity about how to match methods to evaluation questions. The authors address common concerns about RCTs, and the extent to which they are fallacious, and also discuss the challenges of conducting RCTs in informatics and alternative study designs when randomized trials are infeasible.
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